Minneapolis Symphony Orchestra conductor Dimitri Mitropoulous announces that he has taken a position with the New York Philharmonic Orchestra. Antal Dorati is hired to replace him.

Fur trader Alexander Baker receives a patent on a land claim near International Falls.

The Church of the Good Samaritan (Episcopal) in Sauk Centre holds its first service, the wedding of Miss Nellie A. Barrows and Captain Edward Oakford. The church's stained-glass windows had been donated by a friend of Bishop Henry B. Whipple and brought in by oxcart. The west wall of the church would collapse in 1999, destroying two of the original windows. The wall would be rebuilt and the windows replaced by a set from the recently closed Grace Church in Royalton.

Hans Mattson is born in Sweden. An advocate for Swedish immigration to Minnesota, he would establish the Vasa colony in Goodhue County in 1853. He would serve as colonel of the Third Minnesota Regiment during the Civil War and as US consul general in India from 1881 to 1883. In 1877 he would found the Swedish newspaper Minnesota Stats Tidning (Minnesota State Times).

Richard C. Lillehei (brother of C. Walton Lillehei) and William Kelly of the University of Minnesota hospitals perform the world's first successful kidney and pancreas transplant.

The Armistice Day Blizzard strikes, trapping hunters at lakes and drivers on roads. Forty-nine people die when temperatures suddenly drop from the sixties to below zero. Pilot Max Conrad of Winona earns hero honors for taking his Piper Cub up into fifty-mile-per-hour winds to drop supplies and lead rescuers to trapped hunters.

The American Legion, a veterans organization, holds its first convention, in Minneapolis. The convention begins on November 10 and ends on November 12.

The Athenaeum, a structure dedicated to educational lectures and social events for Germans, opens in St. Paul.

Thirteen New Ulm residents establish the state's first chapter of Turnverein. The Turnverein motto is "a sound mind in a sound body," and members sponsor social, educational, and physical events.

The steamboat John Rumsey explodes near the lower levee in St. Paul, killing seven of the crew. Explosions, usually caused by excessive steam pressure, were a common occurrence on Mississippi riverboats.