The Farmers' Alliance in Minnesota thrived from 1886 to 1892. During this time, the organization achieved the most progress toward its political goals in the state. These included greater regulation of the railroad industry as it impacted the wheat market, elimination of irregularities in the grading of wheat, and minimization or elimination of the middleman in the wheat trade.

In forty-six years as a Minnesotan, John Sargent Pillsbury helped establish what eventually became one of the world's largest flour-milling businesses, served three terms as governor, and contributed—generously and often anonymously—to numerous causes he deemed worthy.

Well-connected socially and politically, William Rush Merriam rose through the legislative ranks to become the eleventh governor of Minnesota by age thirty-nine. In 1899, President William McKinley appointed him director of the twelfth national census.

The Knights of Labor shaped business and political policy in Minnesota communities in the late nineteenth century by working with the Farmers' Alliance and advocating for shorter work days, equal pay for women, child labor laws, and cooperation between workers.

Strauss Ice Skates were made by hand at Strauss Skate Shop in St. Paul for almost 100 years. They were popular with professional and amateur skaters in the United States and other countries because of their consistent high quality, which was achieved through a secret hardening process.

John Ireland was ordained a Catholic priest in St. Paul in 1861. By the time he was appointed archbishop of the newly organized Archdiocese of St. Paul in 1888, he was one of the city’s most prominent citizens. Ireland’s causes were many; he is remembered for attracting Irish immigrants to the state, for founding educational institutions, and for establishing the Catholic church in Minnesota.

The Minneapolis, St. Paul and Sault Ste. Marie Railroad, commonly known as the Soo Line from a phonetic spelling of Sault, helped Minnesota farmers and millers prosper by hauling grain directly from Minneapolis to eastern markets.

In June 1922, the Minneapolis Public Library book wagon made its first trip from Minneapolis to Excelsior, a small village on Lake Minnetonka. Riding aboard the book wagon was Gratia Countryman, the library system's visionary director.

Architect Cass Gilbert’s best-known work is the Woolworth Building in New York City, completed in 1913. From 1882 to 1898, however, Gilbert was based in Minnesota, where he designed houses, churches, office buildings, and, most notably, the third Minnesota State Capitol, commissioned in 1895 and completed ten years later.