Lena Olive Smith was a prominent civil rights lawyer and activist during the 1920s and 1930s. She made major contributions toward securing civil rights for minorities in the Twin Cities. Smith began fighting for the rights of others when she became the first African American woman licensed to practice law in Minnesota in 1921. She was the only African American woman to practice law in the state until 1945.

Charlotte Ouisconsin Clark Van Cleve was the child of a military family and a crusader for the rights of disadvantaged people in Minnesota and beyond. Born during her parents' journey to help build the future Fort Snelling, she lived to see a fledgling community grow into an urban center.

The Harrington-Merrill House is the oldest wood-framed structure in Hutchinson and one of the oldest in McLeod County. Lewis Harrington was one of Hutchinson's founders. Harry Merrill, who served as superintendent of schools for thirty-three years, was likely the most important educator in the town's history.

In the late nineteenth century, some of the Jewish immigrants who had originally settled in the Twin Ports of Duluth-Superior saw economic opportunity in the nearby Iron Range of northern Minnesota. From the 1890s through the 1920s they founded retail and service businesses in the region's booming mining towns. Though small in numbers and relatively isolated, Iron Range Jews supported a vibrant communal life through the 1980s, when hard times on the Range led to a general depopulation.

St. Paul's Commerce Building was originally built to house the Commercial Club of St. Paul and the offices of the St. Paul Association of Commerce. Years later, it reflects the economic strength and civic influence of St. Paul's business organizations at the beginning of the twentieth century. The Commerce Building is typical of buildings designed to house commercial and civic groups as well as private tenants.

Minnesota's first experiment in juvenile justice, the State Reform School, operated in St. Paul from 1868 to 1891. During that time, over 1250 inmates, almost all of them boys, were committed to the institution, mostly for petty crimes and "incorrigibility." The school moved to a new facility in Red Wing in 1891.

From 1898 to the early 1930s, St. Paul was the center of a national home furnishings industry based on wire grass, a plant that grew wild in the peat bogs of Minnesota and Wisconsin.

Two of Duluth's oldest Jewish congregations—Temple Emanuel and Tifereth Israel—had little in common after they were founded in the 1890s. While Temple Emanuel was affiliated with Reform Judaism, Tifereth Israel conducted worship services in the Orthodox tradition. Tifereth Israel's 1945 shift to Conservative Judaism, however, coupled with the decline of Duluth's Jewish population, led the two congregations to unite in 1969 as Temple Israel.

When Adas Israel Congregation was founded, in 1885, by Lithuanian immigrants, members met in a house on St. Croix Avenue in what is now the Canal Park area of Duluth. It incorporated in 1899.

The Minnesota State Public School for Dependent and Neglected Children operated from 1886 to 1947. The campus is one of the most intact examples of a state cottage school standing in the United States, and is significant on a national level.