After New York City schoolteacher Harriet Duncan came to Minnesota in 1868, she became an advocate for temperance and women's suffrage. She was president of the Minnesota Woman's Christian Temperance Union (WCTU) for seventeen years and urged the WCTU to work on behalf of women's rights more broadly.

In December 1901, botanist Alexander Pierce Anderson created puffed rice while experimenting with starch crystals in his laboratory. Although he did not yet realize the significance of his discovery, Anderson's new breakfast food would make him a nationally known figure and the face of a Quaker Oats advertising campaign for almost a decade.

The US–Dakota War of 1862 was a turning point in Minnesota history. Joseph Godfrey, an enslaved man, joined the Dakota in their fight against white settler-colonists that summer and fall. He was one of only two African Americans to do so.

Fur trader and translator George Bonga was one of the first Black people born in what later became the state of Minnesota. His mother was Ojibwe, as were both of his wives. Through these relationships, Bonga was part of the mixed racial and cultural groups that connected trading companies and Native Americans. He frequently guided white travelers and traders through the region. Comfortable in many worlds, Bonga often worked as an advocate for the Ojibwe in their dealings with trading companies and the United States government.

Liang May Seen was the first woman of Chinese descent to live in Minnesota. After escaping from a brothel in San Francisco, she learned English, married, and moved to Minneapolis, where she was a leader in the Chinese immigrant community until her death in 1946.

A trustbuster, senator, secretary of state, Nobel laureate, and World Court judge, Frank Kellogg rose from a small farm in Olmsted County to being the highest-ranking diplomat in the United States. He is remembered as one of the authors of the 1928 Pact of Paris, a multi-lateral treaty that renounced aggressive war as a matter of national policy.

Marvel Cooke was a pioneering journalist and political activist who spent her groundbreaking career in a world where she was often the only female African American. Talking about her work environment for the white-owned newspaper the Compass, she told biographer Kay Mills in 1988, ''there were no black workers there and no women."

John Vachon traveled the world as a professional photographer, but the St. Paul native's work was always shaped by his Midwestern upbringing. He is most remembered for his photographs for the Farm Security Administration (FSA) and Look magazine.

Jane Grey Swisshelm lived in Minnesota for only six years, but during that time she left a lasting mark on the state. While in St. Cloud, she founded a newspaper that she used to advocate for women's rights, argue for the abolition of slavery, build up the Republican Party, challenge the authority of the Democratic machine there, and promote violence against Dakota people.

Writer and activist Irene Levine Paull was born in Duluth to Jewish parents. Faced with discrimination because of her ethnicity, gender, and political views, Paull fought for the rights of people who were oppressed.