Swedish immigrant Hans Mattson was a prominent immigration booster and politician. Working for the state and for private companies, he recruited many Swedish and Norwegian immigrants to Minnesota during the late nineteenth century. He was also the first Scandinavian elected to Minnesota office. During his lifetime, Colonel Mattson was one of the best-known Swedish Americans in United States politics.

Artist Alexis Jean Fournier is well known in Minnesota for his atmospheric paintings of Minneapolis and St. Paul landscapes. Fournier is also renowned beyond Minnesota as an important figure in the Arts and Crafts movement.

In the 1880s, agricultural education in Minnesota was in trouble: farmers would not travel to the Twin Cities for classes, and university students did not want to study farming. Oren C. Gregg, a successful dairy farmer from Lyon County, Minnesota, saved the day by bringing lectures directly to Minnesota farmers.

Oliver Hudson Kelley was a "book farmer," a man who had learned what he knew about agriculture from reading rather than from direct experience. In 1867, he helped found the National Grange of the Order of Patrons of Husbandry, the nation's largest agricultural fraternity.

In 1888, a St. Paul Globe exposé of women's working conditions penned by "Eva Gay" launched the career of Eva McDonald Valesh, a young writer. During the time that she lived in the state, Valesh left a big impression on Minnesota journalism, politics, and labor organizing.

The US Congress ordered the beginning of mail service from Superior to Grand Portage, Minnesota, in 1855, but service was spotty. John Beargrease and his brothers came to the rescue. They began covering a regular mail route between Two Harbors and Grand Marais in 1879.

Fredrick Lamar McGhee (1861–1912) was Minnesota’s first African American lawyer, its most consequential early civil rights leader, the only Minnesota public figure born in slavery, a renowned orator, and a criminal defense lawyer famous for his courtroom victories. His civil rights work had national reverberations. His break with Booker T. Washington and subsequent alliance with W. E. B. DuBois led to the foundation of the Niagara Movement, and then the NAACP.

Dr. Martha Ripley was an early advocate for women's health and welfare. She and her family moved to Minneapolis in 1883, just after she completed medical training at Boston University School of Medicine.

The National Baseball Hall of Fame credits Charles Albert Bender with inventing the slider, a curveball with extra speed. Like his patented pitch, Bender's life course was a circuitous one, beginning on the White Earth Reservation in northern Minnesota.

Multi-talented artist, designer, teacher, and author Henrietta Barclay Paist is perhaps best known for her china painting, a popular turn-of-the-century pastime. Born in Red Wing in 1870, she studied ceramics in Germany, watercolor painting in Minneapolis, and design in Chicago before settling in the Twin Cities.